Reviewed by Dr. Jason Wright, D.O. · September 23, 2026
The science
How it works
Native to gastric juice
BPC-157 is a fragment of a protein found in human gastric juice and stays stable in stomach acid, so it survives the trip to where it works.
Protects the gut lining
In animal studies it protected and healed the lining of the esophagus, stomach, and intestine, including damage from alcohol and NSAIDs.
Builds new blood vessels
It drives new blood vessel growth, bringing circulation to damaged tissue so it can repair.
Works through nitric oxide
Acts on the nitric oxide system that controls blood flow and healing in the gut wall.
Most of this comes from animal research. An early human program in ulcerative colitis reported it was well tolerated, but oral capsules have not been studied in people.
Dosing
Your dosing plan
Dr. Wright sets your exact dose within this range at your visit.
Standard protocol
FormOral capsule
Dose500 mcg (1 capsule)
ScheduleOnce daily
Based onPharmacy labeling, animal studies
Course
Form—
Dose4 to 8 weeks
ScheduleThen review with Dr. Wright
Based onClinical practice
Pairs with
FormOral capsule
DoseKPV capsules
ScheduleTaken together, once daily
Based onClinical convention
Side effects
Side effects and what to expect
Mild stomach upsetUncommon · First doses
Usually passes. Let us know if it doesn’t.
HeadacheUncommon · First week
Stay hydrated.
Allergic reactionRare · Any time
Stop and contact the practice.
A note from Dr. Wright
BPC-157 was first found in gastric juice, and it stays stable there, which is why the capsule makes sense for gut problems. For tendons and joints I still prefer the injection. For the gut, I start here, usually paired with KPV.
Dr. Jason Wright, D.O. · Board certified, American Board of Cosmetic Surgery
Cost & access
Getting started with BPC-157 Capsules
BPC-157 Capsules
500 mcg capsules, 30 per bottle · one capsule a day · Labeled in your name
