Reviewed by Dr. Jason Wright, D.O. · September 23, 2026
The science
How it works
Prepares the pulse (tesamorelin)
A stabilized GHRH that resists breakdown.
Triggers it (ipamorelin)
Acts on the ghrelin receptor to release growth hormone.
Targets visceral fat
Growth hormone preferentially mobilizes deep abdominal fat.
Keeps feedback intact
Your own controls still set the ceiling.
Tesamorelin’s visceral-fat data comes from randomized human trials. The combination itself is clinical convention.
Dosing
Your dosing plan
Dr. Wright sets your exact dose within this range at your visit.
Starting dose
FormSubcutaneous, bedtime
Dose42 units (1 mg tesamorelin, 500 mcg ipamorelin)
ScheduleNightly, 4 weeks
Based onProtocol
Standard dose
FormSubcutaneous, bedtime
Dose83 units (2 mg tesamorelin, 1 mg ipamorelin)
ScheduleNightly, 8 more weeks
Based onFDA-labeled tesamorelin dose
Lower-cost option
FormTesamorelin alone, 15 mg vial
Dose2 mg (67 units)
ScheduleAbout $20 a dose instead of $30
Based onSame tesamorelin dose, without ipamorelin
Course
Form—
Dose12 weeks
ScheduleThen reassess
Based onClinical practice
Side effects
Side effects and what to expect
Redness or itching at the injection siteCommon · First few weeks
Rotate sites.
Joint aches or swellingUncommon · Any time
Let us know. The dose may need to come down.
Numbness or tingling in the handsUncommon · Any time
Let us know promptly.
Rising blood sugarUncommon · Seen on labs
Dr. Wright monitors this and adjusts your dose.
A note from Dr. Wright
Visceral fat sits behind the abdominal wall, where surgery cannot address it. This combination targets it while preserving your own growth hormone rhythm.
Dr. Jason Wright, D.O. · Board certified, American Board of Cosmetic Surgery
Cost & access
Getting started with Tesamorelin / Ipamorelin
Tesamorelin / Ipamorelin
Tesamorelin 2.4 mg/mL + ipamorelin 1.2 mg/mL in one 5 mL vial · Labeled in your name
